Lexington Medical Center Lexington Medical Center is located on 338 E Columbia Ave in Leesville. They can be reached by phone by calling (803) 604-0066 . Their hours of operation are Monday 8:00am to 7:00pm , Tuesday 8:00am to 7:00pm , Wednesday 8:00am to 7:00pm , Thursday 8:00am to 7:00pm , Friday 8:00am to 5:00pm , Saturday 8:00am to 5:00pm and they can be reached by calling (803) 604-0066 . They have a single review on MojoPages.com, and it's a positive review.