Comfort Inn at Irvine Spectrum is located on 23061 Avenida De La Carlota in Laguna Hills. Comfort Inn at Irvine Spectrum offers a number of products and services, which include Wireless, Business Center . Comfort Inn at Irvine Spectrum accepts Cash, Diners, Visa, American Express, Discover. as methods of payment. Comfort Inn at Irvine Spectrum can be reached by phone by calling (949) 859-0166 during the hours which are Monday 24 hours , Tuesday 24 hours , Wednesday 24 hours , Thursday 24 hours , Friday 24 hours , Saturday 24 hours , Sunday 24 hours . Comfort Inn at Irvine Spectrum has a total of 17 reviews, 10 positive reviews and 5 negative reviews.